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mTORC1 inhibition in the nucleus accumbens 'protects' against the expression of drug seeking and 'relapse' and is associated with reductions in GluA1 AMPAR and CAMKIIα levels.
James, Morgan H; Quinn, Rikki K; Ong, Lin Kooi; Levi, Emily M; Charnley, Janine L; Smith, Doug W; Dickson, Phillip W; Dayas, Christopher V.
Afiliación
  • James MH; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Quinn RK; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Ong LK; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Levi EM; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Charnley JL; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Smith DW; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Dickson PW; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
  • Dayas CV; Neurobiology of Addiction Laboratory, School of Biomedical Sciences and Pharmacy and the Centre for Translational Neuroscience and Mental Health Research, University of Newcastle and the Hunter Medical Research Institute, Newcastle, NSW, Australia.
Neuropsychopharmacology ; 39(7): 1694-702, 2014 Jun.
Article en En | MEDLINE | ID: mdl-24469593
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores AMPA / Sirolimus / Complejos Multiproteicos / Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina / Serina-Treonina Quinasas TOR / Comportamiento de Búsqueda de Drogas / Núcleo Accumbens Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Neuropsychopharmacology Asunto de la revista: NEUROLOGIA / PSICOFARMACOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Australia
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Receptores AMPA / Sirolimus / Complejos Multiproteicos / Proteína Quinasa Tipo 2 Dependiente de Calcio Calmodulina / Serina-Treonina Quinasas TOR / Comportamiento de Búsqueda de Drogas / Núcleo Accumbens Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: Neuropsychopharmacology Asunto de la revista: NEUROLOGIA / PSICOFARMACOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Australia