[Targeted genome modifications using TALEN]. / L'ingénierie des génomes par les TALEN.
Med Sci (Paris)
; 30(2): 186-93, 2014 Feb.
Article
en Fr
| MEDLINE
| ID: mdl-24572118
ABSTRACT
Precise modifications of genomes have been one of the biggest goals in the fields of biotechnology and biomedical research. Recent discovery of TALE (transcription activator-like effectors) and the engineering of customized TALEN (transcription activator-like effector nucleases) allowed rapid genome editing in a variety of cell types and different model organisms. TALEN are molecular scissors used to induce a wide range of specific and efficient genomic modifications. TALEN promise to have profound impacts on biological and medical research over the coming years.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Ingeniería Genética
/
Activación Transcripcional
/
Endonucleasas
Límite:
Animals
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Humans
Idioma:
Fr
Revista:
Med Sci (Paris)
Asunto de la revista:
MEDICINA
Año:
2014
Tipo del documento:
Article
País de afiliación:
Francia