[Molecular lymph node staging in prostate and bladder cancer]. / Molekulares Lymphknotenstaging beim Prostata- und Harnblasenkarzinom.
Urologe A
; 53(4): 484-90, 2014 Apr.
Article
en De
| MEDLINE
| ID: mdl-24671247
ABSTRACT
A positive lymph node status is a major prognostic factor for tumor recurrence and mortality following radical prostatectomy in prostate cancer patients or radical cystectomy in bladder cancer patients. However, despite having histopathologic negative lymph nodes, a substantial proportion of patient suffers from tumor recurrence within a few years after the operation. Tumor recurrence in node-negative patients may result from hematogeneous or lymphatic metastatic spread which remains undetected by standard clinical or histopathologic examinations. Molecular lymph node analysis is a potential method for detection of lymph node metastases with higher sensitivity and for prognostic risk stratification of patients with histopathologic negative lymph nodes.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Neoplasias de la Próstata
/
Neoplasias de la Vejiga Urinaria
/
Técnicas de Diagnóstico Molecular
/
Metástasis Linfática
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
Límite:
Humans
/
Male
Idioma:
De
Revista:
Urologe A
Año:
2014
Tipo del documento:
Article