Plasmid carriage of bla NDM-1 in clinical Acinetobacter baumannii isolates from India.
Antimicrob Agents Chemother
; 58(7): 4211-3, 2014 Jul.
Article
en En
| MEDLINE
| ID: mdl-24752257
ABSTRACT
NDM-1 probably emerged in Acinetobacter species prior to its dissemination among Enterobacteriaceae, and NDM-1-like enzymes are increasingly reported in Acinetobacter species. Here, we report on the genetic context of blaNDM-1 in the earliest known NDM-1-producing organisms, clinical isolates of Acinetobacter from India in 2005. These strains harbor blaNDM-1 plasmids of different sizes. The gene is associated with the remnants of the Tn125 transposon normally associated with blaNDM-1 in Acinetobacter spp. The transposon has been disrupted by the IS26 insertion and subsequent movement events.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Plásmidos
/
Beta-Lactamasas
/
Acinetobacter baumannii
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
En
Revista:
Antimicrob Agents Chemother
Año:
2014
Tipo del documento:
Article
País de afiliación:
Reino Unido