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Estradiol promotes pentose phosphate pathway addiction and cell survival via reactivation of Akt in mTORC1 hyperactive cells.
Sun, Y; Gu, X; Zhang, E; Park, M-A; Pereira, A M; Wang, S; Morrison, T; Li, C; Blenis, J; Gerbaudo, V H; Henske, E P; Yu, J J.
Afiliación
  • Sun Y; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Gu X; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Zhang E; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Park MA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Pereira AM; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Wang S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Morrison T; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Li C; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Blenis J; Department of Cell Biology, Harvard Medical School, Boston, MA 02115, USA.
  • Gerbaudo VH; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Henske EP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
  • Yu JJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, 1 Blackfan Circle, 6th Floor, Boston, MA 02115, USA.
Cell Death Dis ; 5: e1231, 2014 May 15.
Article en En | MEDLINE | ID: mdl-24832603
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vía de Pentosa Fosfato / Neoplasias de la Mama / Linfangioleiomiomatosis / Complejos Multiproteicos / Estradiol / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Death Dis Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Vía de Pentosa Fosfato / Neoplasias de la Mama / Linfangioleiomiomatosis / Complejos Multiproteicos / Estradiol / Proteínas Proto-Oncogénicas c-akt / Serina-Treonina Quinasas TOR Tipo de estudio: Prognostic_studies Idioma: En Revista: Cell Death Dis Año: 2014 Tipo del documento: Article País de afiliación: Estados Unidos