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Toward a high-throughput screening platform for directed evolution of enzymes that activate genotoxic prodrugs.
Copp, J N; Williams, E M; Rich, M H; Patterson, A V; Smaill, J B; Ackerley, D F.
Afiliación
  • Copp JN; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand Present address: Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
  • Williams EM; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.
  • Rich MH; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand.
  • Patterson AV; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand Auckland Cancer Society Research Centre, University of Auckland, Grafton, Auckland 1023, New Zealand.
  • Smaill JB; Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Auckland 1010, New Zealand Auckland Cancer Society Research Centre, University of Auckland, Grafton, Auckland 1023, New Zealand.
  • Ackerley DF; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand Centre for Biodiscovery, Victoria University of Wellington, Wellington 6012, New Zealand Maurice Wilkins Centre for Molecular Biodiscovery, School of Biological Sciences, University of Auckland, Auckland 1
Protein Eng Des Sel ; 27(10): 399-403, 2014 Oct.
Article en En | MEDLINE | ID: mdl-24996412

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Profármacos / Ingeniería de Proteínas / Evolución Molecular Dirigida / Enzimas / Ensayos Analíticos de Alto Rendimiento / Mutágenos Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Protein Eng Des Sel Asunto de la revista: BIOQUIMICA / BIOTECNOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Canadá

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Profármacos / Ingeniería de Proteínas / Evolución Molecular Dirigida / Enzimas / Ensayos Analíticos de Alto Rendimiento / Mutágenos Tipo de estudio: Diagnostic_studies / Screening_studies Idioma: En Revista: Protein Eng Des Sel Asunto de la revista: BIOQUIMICA / BIOTECNOLOGIA Año: 2014 Tipo del documento: Article País de afiliación: Canadá