67-kDa laminin receptor-dependent protein phosphatase 2A (PP2A) activation elicits melanoma-specific antitumor activity overcoming drug resistance.

Tsukamoto, Shuntaro; Huang, Yuhui; Umeda, Daisuke; Yamada, Shuhei; Yamashita, Shuya; Kumazoe, Motofumi; Kim, Yoonhee; Murata, Motoki; Yamada, Koji; Tachibana, Hirofumi

Tsukamoto, Shuntaro; Huang, Yuhui; Umeda, Daisuke; Yamada, Shuhei; Yamashita, Shuya; Kumazoe, Motofumi; Kim, Yoonhee; Murata, Motoki; Yamada, Koji; Tachibana, Hirofumi.

Afiliación

Tsukamoto S; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Huang Y; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Umeda D; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Yamada S; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Yamashita S; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Kumazoe M; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Kim Y; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Murata M; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Yamada K; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and.
Tachibana H; From the Division of Applied Biological Chemistry, Department of Bioscience and Biotechnology, Faculty of Agriculture and Food Functional Design Research Center, Kyushu University, Fukuoka 812-8581, Japan tatibana@agr.kyushu-u.ac.jp.

J Biol Chem ; 289(47): 32671-81, 2014 Nov 21.

Article en En | MEDLINE | ID: mdl-25294877

Asunto(s)

Catequina/análogos & derivados; Resistencia a Antineoplásicos/efectos de los fármacos; Melanoma/tratamiento farmacológico; Proteína Fosfatasa 2/metabolismo; Receptores de Laminina/metabolismo; Animales; Western Blotting; Catequina/farmacología; Línea Celular Tumoral; Proliferación Celular/efectos de los fármacos; Células Cultivadas; Proteínas de Unión al ADN; Activación Enzimática; Femenino; Chaperonas de Histonas/genética; Chaperonas de Histonas/metabolismo; Humanos; Indoles/farmacología; Melanoma/genética; Melanoma/metabolismo; Ratones Endogámicos BALB C; Ratones Endogámicos C57BL; Ratones Desnudos; Microscopía Confocal; Mutación; Neurofibromina 2/genética; Neurofibromina 2/metabolismo; Proteína Fosfatasa 2/genética; Proteínas Proto-Oncogénicas B-raf/antagonistas & inhibidores; Proteínas Proto-Oncogénicas B-raf/genética; Proteínas Proto-Oncogénicas B-raf/metabolismo; Interferencia de ARN; Receptores de Laminina/genética; Sulfonamidas/farmacología; Serina-Treonina Quinasas TOR/metabolismo; Factores de Transcripción/genética; Factores de Transcripción/metabolismo; Ensayos Antitumor por Modelo de Xenoinjerto

Palabras clave

Adenylate Cyclase (Adenylyl Cyclase); Cancer Chemoprevention; Melanoma; Membrane Protein; Polyphenol; Protein Phosphatase 2 (PP2A); Second Messenger

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Catequina / Receptores de Laminina / Resistencia a Antineoplásicos / Proteína Fosfatasa 2 / Melanoma Tipo de estudio: Prognostic_studies Idioma: En Revista: J Biol Chem Año: 2014 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google