Loss of c-REL but not NF-&#954;B2 prevents autoimmune disease driven by FasL mutation.

O'Reilly, L A; Hughes, P; Lin, A; Waring, P; Siebenlist, U; Jain, R; Gray, D H D; Gerondakis, S; Strasser, A

Loss of c-REL but not NF-κB2 prevents autoimmune disease driven by FasL mutation.

O'Reilly, L A; Hughes, P; Lin, A; Waring, P; Siebenlist, U; Jain, R; Gray, D H D; Gerondakis, S; Strasser, A.

Afiliación

O'Reilly LA; 1] Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia [2] Department of Medical Biology, The University of Melbourne, Parkville 3010, Victoria, Australia.
Hughes P; 1] Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia [2] Department of Nephrology, The Royal Melbourne Hospital, Parkville 3052, Victoria, Australia.
Lin A; Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia.
Waring P; Department of Pathology, The University of Melbourne, Parkville 3010 Victoria, Australia.
Siebenlist U; Laboratory of Molecular Immunology, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, USA.
Jain R; 1] Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia [2] Department of Medical Biology, The University of Melbourne, Parkville 3010, Victoria, Australia.
Gray DH; 1] Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia [2] Department of Medical Biology, The University of Melbourne, Parkville 3010, Victoria, Australia.
Gerondakis S; Australian Centre for Blood Diseases and Department of Clinical Hematology, Monash University Central Clinical School, Melbourne 3004, Victoria, Australia.
Strasser A; 1] Molecular Genetics of Cancer Division, The Walter and Eliza Hall Institute of Medical Research, Parkville 3052, Victoria, Australia [2] Department of Medical Biology, The University of Melbourne, Parkville 3010, Victoria, Australia.

Cell Death Differ ; 22(5): 767-78, 2015 May.

Article en En | MEDLINE | ID: mdl-25361085

Asunto(s)

Enfermedades Autoinmunes/metabolismo; Proteína Ligando Fas/metabolismo; Mutación; Subunidad p52 de NF-kappa B/metabolismo; Proteínas Proto-Oncogénicas c-rel/metabolismo; Receptor fas/metabolismo; Animales; Enfermedades Autoinmunes/genética; Enfermedades Autoinmunes/patología; Enfermedades Autoinmunes/prevención & control; Proteína Ligando Fas/genética; Ratones; Ratones Noqueados; Subunidad p52 de NF-kappa B/genética; Proteínas Proto-Oncogénicas c-rel/genética; Transducción de Señal/genética; Receptor fas/genética

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Enfermedades Autoinmunes / Receptor fas / Proteínas Proto-Oncogénicas c-rel / Subunidad p52 de NF-kappa B / Proteína Ligando Fas / Mutación Límite: Animals Idioma: En Revista: Cell Death Differ Año: 2015 Tipo del documento: Article País de afiliación: Australia

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