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Adaptation of pandemic H2N2 influenza A viruses in humans.
Joseph, Udayan; Linster, Martin; Suzuki, Yuka; Krauss, Scott; Halpin, Rebecca A; Vijaykrishna, Dhanasekaran; Fabrizio, Thomas P; Bestebroer, Theo M; Maurer-Stroh, Sebastian; Webby, Richard J; Wentworth, David E; Fouchier, Ron A M; Bahl, Justin; Smith, Gavin J D.
Afiliación
  • Joseph U; Duke-NUS Graduate Medical School, Singapore.
  • Linster M; Duke-NUS Graduate Medical School, Singapore Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Suzuki Y; Duke-NUS Graduate Medical School, Singapore.
  • Krauss S; Virology Division, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Halpin RA; J. Craig Venter Institute, Rockville, Maryland, USA.
  • Vijaykrishna D; Duke-NUS Graduate Medical School, Singapore Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
  • Fabrizio TP; Virology Division, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Bestebroer TM; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Maurer-Stroh S; Bioinformatics Institute, Agency for Science, Technology and Research, Singapore School of Biological Sciences, Nanyang Technological University, Singapore.
  • Webby RJ; Virology Division, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Wentworth DE; J. Craig Venter Institute, Rockville, Maryland, USA.
  • Fouchier RA; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
  • Bahl J; Duke-NUS Graduate Medical School, Singapore Center for Infectious Diseases, The University of Texas School of Public Health, Houston, Texas, USA Justin.Bahl@uth.tmc.edu gavin.smith@duke-nus.edu.sg.
  • Smith GJ; Duke-NUS Graduate Medical School, Singapore Duke Global Health Institute, Duke University, Durham, North Carolina, USA Justin.Bahl@uth.tmc.edu gavin.smith@duke-nus.edu.sg.
J Virol ; 89(4): 2442-7, 2015 Feb.
Article en En | MEDLINE | ID: mdl-25505070
ABSTRACT
The 1957 A/H2N2 influenza virus caused an estimated 2 million fatalities during the pandemic. Since viruses of the H2 subtype continue to infect avian species and pigs, the threat of reintroduction into humans remains. To determine factors involved in the zoonotic origin of the 1957 pandemic, we performed analyses on genetic sequences of 175 newly sequenced human and avian H2N2 virus isolates and all publicly available influenza virus genomes.
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Adaptación Biológica / Zoonosis / Gripe Humana / Subtipo H2N2 del Virus de la Influenza A / Gripe Aviar Límite: Animals / Humans Idioma: En Revista: J Virol Año: 2015 Tipo del documento: Article País de afiliación: Singapur
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Adaptación Biológica / Zoonosis / Gripe Humana / Subtipo H2N2 del Virus de la Influenza A / Gripe Aviar Límite: Animals / Humans Idioma: En Revista: J Virol Año: 2015 Tipo del documento: Article País de afiliación: Singapur