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Anti-vascular endothelial growth factor treatment normalizes tuberculosis granuloma vasculature and improves small molecule delivery.
Datta, Meenal; Via, Laura E; Kamoun, Walid S; Liu, Chong; Chen, Wei; Seano, Giorgio; Weiner, Danielle M; Schimel, Daniel; England, Kathleen; Martin, John D; Gao, Xing; Xu, Lei; Barry, Clifton E; Jain, Rakesh K.
Afiliación
  • Datta M; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114; Department of Chemical and Biological Engineering, Tufts University, Medford, MA 02155;
  • Via LE; Tuberculosis Research Section, Laboratory of Clinical Infectious Disease, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892;
  • Kamoun WS; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;
  • Liu C; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;
  • Chen W; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;
  • Seano G; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;
  • Weiner DM; Tuberculosis Research Section, Laboratory of Clinical Infectious Disease, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892;
  • Schimel D; Tuberculosis Research Section, Laboratory of Clinical Infectious Disease, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892;
  • England K; Tuberculosis Research Section, Laboratory of Clinical Infectious Disease, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892;
  • Martin JD; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139; and.
  • Gao X; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;
  • Xu L; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114;
  • Barry CE; Tuberculosis Research Section, Laboratory of Clinical Infectious Disease, National Institute of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD 20892; Department of Clinical Laboratory Sciences, Faculty of Health Sciences, University of Cape Town, Rondebosch 7701, South A
  • Jain RK; Edwin L. Steele Laboratory for Tumor Biology, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114; cbarry@mail.nih.gov jain@steele.mgh.harvard.edu.
Proc Natl Acad Sci U S A ; 112(6): 1827-32, 2015 Feb 10.
Article en En | MEDLINE | ID: mdl-25624495
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tuberculosis / Vasos Sanguíneos / Granuloma del Sistema Respiratorio / Factor A de Crecimiento Endotelial Vascular / Anticuerpos Monoclonales Humanizados Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tuberculosis / Vasos Sanguíneos / Granuloma del Sistema Respiratorio / Factor A de Crecimiento Endotelial Vascular / Anticuerpos Monoclonales Humanizados Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2015 Tipo del documento: Article