Portal vein reconstruction in adult living donor liver transplantation for patients with portal vein thrombosis in single center experience.
J Hepatobiliary Pancreat Sci
; 22(6): 467-74, 2015 Jun.
Article
en En
| MEDLINE
| ID: mdl-25755116
ABSTRACT
BACKGROUND:
Liver transplantation (LT) used to be contraindicated in patients with portal vein thrombosis (PVT). In comparison to deceased donor LT, living donor LT (LDLT) still presents additional difficulties in determining appropriate vein grafts and overcoming small-for-size syndrome. Here, we introduce our LDLT strategies and assess their outcomes in adult patients with pre-existing PVT.METHODS:
We performed 282 consecutive adult LDLTs between April 2006 and December 2011. Forty-eight patients (17%) had pre-existing PVT (grade I; 15, II; 20, III; 12, IV; 1).RESULTS:
Our preferred treatments for PVT were thrombectomies/thromboendovenectomies in 30 patients, replaced grafts in seven, jump grafts in seven, renoportal anastomosis in one and no surgical intervention owing to minimal thrombosis in three. Post-transplant portal vein complications occurred in eight of 48 (17%) cases, which were treated by surgery, anticoagulation therapy, and/or interventional radiology. Post-transplant survival rates of patients with preexisting PVT at 1 year and 5 years were comparable to a PVT-free cohort (1 year; 81% vs. 77%, 5 years; 81% vs. 73%).CONCLUSIONS:
The excellent survival rates in patients with PVT who underwent LDLT could be attributed to our strategies, which included surgical techniques and timely treatment of postoperative complications.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Vena Porta
/
Procedimientos Quirúrgicos Vasculares
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Trasplante de Hígado
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Donadores Vivos
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Procedimientos de Cirugía Plástica
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Trombosis de la Vena
Tipo de estudio:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Hepatobiliary Pancreat Sci
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón