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An in vivo chemical genetic screen identifies phosphodiesterase 4 as a pharmacological target for hedgehog signaling inhibition.
Williams, Charles H; Hempel, Jonathan E; Hao, Jijun; Frist, Audrey Y; Williams, Michelle M; Fleming, Jonathan T; Sulikowski, Gary A; Cooper, Michael K; Chiang, Chin; Hong, Charles C.
Afiliación
  • Williams CH; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Cell and Developmental Biology, Vanderbilt University School
  • Hempel JE; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Hao J; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; College of Veterinary Medicine, Western University of Health Sciences, Pomona, CA 91766, USA.
  • Frist AY; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Williams MM; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Fleming JT; Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Sulikowski GA; Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Department of Chemistry, Vanderbilt University, Nashville, TN 37235, USA.
  • Cooper MK; Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Research Medicine, Veterans Affairs Tennessee Valley Healthcare System, Nashville, TN 37212, USA.
  • Chiang C; Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Hong CC; Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Cell and Developmental Biology, Vanderbilt University School
Cell Rep ; 11(1): 43-50, 2015 Apr 07.
Article en En | MEDLINE | ID: mdl-25818300
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinonas / Tiofenos / Proteínas Quinasas Dependientes de AMP Cíclico / Proteínas de Pez Cebra / Receptores Acoplados a Proteínas G / Fosfodiesterasas de Nucleótidos Cíclicos Tipo 4 / Inhibidores de Fosfodiesterasa 4 Límite: Animals Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinonas / Tiofenos / Proteínas Quinasas Dependientes de AMP Cíclico / Proteínas de Pez Cebra / Receptores Acoplados a Proteínas G / Fosfodiesterasas de Nucleótidos Cíclicos Tipo 4 / Inhibidores de Fosfodiesterasa 4 Límite: Animals Idioma: En Revista: Cell Rep Año: 2015 Tipo del documento: Article