[Contribution of central hospital laboratory to critical bleeding].
Rinsho Byori
; 62(12): 1286-94, 2014 Dec.
Article
en Ja
| MEDLINE
| ID: mdl-25823248
ABSTRACT
It has been reported that fibrinogen products, such as fibrinogen concentrates, cryoprecipitate (CRYO), and fresh frozen plasma, are beneficial for treating coagulopathy due to massive blood transfusion. For the appropriate use of these products, it is necessary to evaluate the status of coagulopathy and determine the trigger level of the fibrinogen concentration for the administration of fibrinogen products. In our institution, we established a treatment procedure for coagulopathy due to massive transfusion in 2011. This procedure includes determination of the trigger level for administration of CRYO (150 mg/dL), timing of sample collection for the evaluation of coagulation parameters (prothrombin time, activated partial thromboplastin time, and fibrinogen) and concentration status during the operation, and a method for rapid coagulation testing (turnaround time within 15 minutes) in critical bleeding. Since 2011, we have performed 56 rapid coagulation tests for patients suffering from critical bleeding. The average turnover time was 13 minutes. According to the rapid coagulation test results, CRYO was administered to 27 patients. These results are satisfactory for treating critical bleeding patients. We stress the need for the establishment of a rapid coagulation test system in the central hospital laboratory. (Review).
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Base de datos:
MEDLINE
Asunto principal:
Transfusión Sanguínea
/
Laboratorios de Hospital
/
Pérdida de Sangre Quirúrgica
/
Hemorragia
Límite:
Humans
País/Región como asunto:
Asia
Idioma:
Ja
Revista:
Rinsho Byori
Año:
2014
Tipo del documento:
Article