HIV vaccine research: the challenge and the way forward.
J Immunol Res
; 2015: 503978, 2015.
Article
en En
| MEDLINE
| ID: mdl-25861656
ABSTRACT
Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) is a worldwide epidemic, with over 35 million people infected currently. Therefore, the development of a safe and effective HIV-1 vaccine is on top of the global health priority. In the past few years, there have been many promising advances in the prevention of HIV/AIDS, among which the RV144 Thai trial has been encouraging and suggests optimization of the current vaccine strategies or search for novel strategies. Here we reviewed the brief history of HIV-1 vaccine, analyzed key challenges existing now, and illustrated future research priority/directions for a therapeutic or prophylactic HIV-1 vaccine, with the hope of accelerating the speed of vaccine development. We believe that an effective HIV-1 vaccine, together with other prevention approaches, will bring an end to this epidemic in the near future.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Investigación
/
Infecciones por VIH
/
Vacunas contra el SIDA
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Immunol Res
Año:
2015
Tipo del documento:
Article
País de afiliación:
China