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Efficient access to novel androsteno-17-(1',3',4')-oxadiazoles and 17ß-(1',3',4')-thiadiazoles via N-substituted hydrazone and N,N'-disubstituted hydrazine intermediates, and their pharmacological evaluation in vitro.
Kovács, Dóra; Wölfling, János; Szabó, Nikoletta; Szécsi, Mihály; Minorics, Renáta; Zupkó, István; Frank, Éva.
Afiliación
  • Kovács D; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
  • Wölfling J; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
  • Szabó N; 1st Department of Medicine, University of Szeged, Korányi fasor 8-10, H-6720 Szeged, Hungary.
  • Szécsi M; 1st Department of Medicine, University of Szeged, Korányi fasor 8-10, H-6720 Szeged, Hungary.
  • Minorics R; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
  • Zupkó I; Department of Pharmacodynamics and Biopharmacy, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
  • Frank É; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary. Electronic address: frank@chem.u-szeged.hu.
Eur J Med Chem ; 98: 13-29, 2015 Jun 15.
Article en En | MEDLINE | ID: mdl-25993309
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Oxadiazoles / Tiadiazoles / Hidrazinas / Hidrazonas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2015 Tipo del documento: Article País de afiliación: Hungria
Texto completo
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XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Oxadiazoles / Tiadiazoles / Hidrazinas / Hidrazonas Límite: Humans Idioma: En Revista: Eur J Med Chem Año: 2015 Tipo del documento: Article País de afiliación: Hungria