Paclitaxel pretreatment overcomes hypoxia inducible factor-1&#945;-induced radioresistance acquisition of human hepatoma and lung adenocarcinoma cells.

Lai, Kun-Goung; Lin, Yi-Hsien; Ho, Chun-Te; Chen, Chun-Yi; Peng, Chu-Ying; Liu, Tsan-Zon; Chiou, Jeng-Fong

Paclitaxel pretreatment overcomes hypoxia inducible factor-1α-induced radioresistance acquisition of human hepatoma and lung adenocarcinoma cells.

Lai, Kun-Goung; Lin, Yi-Hsien; Ho, Chun-Te; Chen, Chun-Yi; Peng, Chu-Ying; Liu, Tsan-Zon; Chiou, Jeng-Fong.

Afiliación

Lai KG; Department of Radiation Oncology, Tungs' Taichung Metro Harbor Hospital, Taichung, Taiwan.
Lin YH; Division of Radiotherapy, Cheng Hsin General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Ho CT; Graduate Institute of Medical Sciences, Taipei Medical University, Taipei, Taiwan.
Chen CY; Department of Hemato-Oncology, Taichung Hospital, Ministry of Health and Welfare, Taichung, Taiwan.
Peng CY; Cardiovascular Center and Department of Anesthesiology, Taichung Veteran General Hospital, Taichung, Taiwan.
Liu TZ; Department of Radiation Oncology, Taipei Medical University and Hospital, Taipei, Taiwan. Electronic address: tzliu@h.tmu.edu.tw.
Chiou JF; Department of Radiation Oncology, Taipei Medical University and Hospital, Taipei, Taiwan; Department of Radiation Oncology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Electronic address: solomanc@tmu.edu.tw.

Life Sci ; 136: 7-12, 2015 Sep 01.

Article en En | MEDLINE | ID: mdl-26135626

Asunto(s)

Antineoplásicos Fitogénicos/farmacología; Subunidad alfa del Factor 1 Inducible por Hipoxia/fisiología; Paclitaxel/farmacología; Tolerancia a Radiación/efectos de los fármacos; Adenocarcinoma; Adenocarcinoma del Pulmón; Carcinoma Hepatocelular; Línea Celular Tumoral; Supervivencia Celular/efectos de los fármacos; Supervivencia Celular/efectos de la radiación; Ensayos de Selección de Medicamentos Antitumorales; Humanos; Neoplasias Hepáticas; Neoplasias Pulmonares; Transducción de Señal

Palabras clave

BFGF/PI3K/Akt pathway; HIF-1α; Paclitaxel; Radiosensitization

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Tolerancia a Radiación / Paclitaxel / Subunidad alfa del Factor 1 Inducible por Hipoxia / Antineoplásicos Fitogénicos Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Life Sci Año: 2015 Tipo del documento: Article País de afiliación: Taiwán

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