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An Oncogenic NTRK Fusion in a Patient with Soft-Tissue Sarcoma with Response to the Tropomyosin-Related Kinase Inhibitor LOXO-101.
Doebele, Robert C; Davis, Lara E; Vaishnavi, Aria; Le, Anh T; Estrada-Bernal, Adriana; Keysar, Stephen; Jimeno, Antonio; Varella-Garcia, Marileila; Aisner, Dara L; Li, Yali; Stephens, Philip J; Morosini, Deborah; Tuch, Brian B; Fernandes, Michele; Nanda, Nisha; Low, Jennifer A.
Afiliación
  • Doebele RC; University of Colorado Cancer Center, Aurora, Colorado. robert.doebele@ucdenver.edu.
  • Davis LE; Oregon Health and Science University Knight Cancer Institute, Portland, Oregon.
  • Vaishnavi A; University of Colorado Cancer Center, Aurora, Colorado.
  • Le AT; University of Colorado Cancer Center, Aurora, Colorado.
  • Estrada-Bernal A; University of Colorado Cancer Center, Aurora, Colorado.
  • Keysar S; University of Colorado Cancer Center, Aurora, Colorado.
  • Jimeno A; University of Colorado Cancer Center, Aurora, Colorado.
  • Varella-Garcia M; University of Colorado Cancer Center, Aurora, Colorado.
  • Aisner DL; University of Colorado Cancer Center, Aurora, Colorado.
  • Li Y; Foundation Medicine, Cambridge, Massachusetts.
  • Stephens PJ; Foundation Medicine, Cambridge, Massachusetts.
  • Morosini D; Foundation Medicine, Cambridge, Massachusetts.
  • Tuch BB; Loxo Oncology, South San Francisco, California.
  • Fernandes M; Loxo Oncology, South San Francisco, California.
  • Nanda N; Loxo Oncology, South San Francisco, California.
  • Low JA; Loxo Oncology, South San Francisco, California.
Cancer Discov ; 5(10): 1049-57, 2015 Oct.
Article en En | MEDLINE | ID: mdl-26216294
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Sarcoma / Proteínas de Fusión Oncogénica / Proteínas Oncogénicas / Inhibidores de Proteínas Quinasas / Antineoplásicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies Límite: Adult / Female / Humans Idioma: En Revista: Cancer Discov Año: 2015 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Sarcoma / Proteínas de Fusión Oncogénica / Proteínas Oncogénicas / Inhibidores de Proteínas Quinasas / Antineoplásicos Tipo de estudio: Clinical_trials / Diagnostic_studies / Prognostic_studies Límite: Adult / Female / Humans Idioma: En Revista: Cancer Discov Año: 2015 Tipo del documento: Article