Effects of telephone-delivered lifestyle support on the development of diabetes in participants at high risk of type 2 diabetes: J-DOIT1, a pragmatic cluster randomised trial.
BMJ Open
; 5(8): e007316, 2015 Aug 19.
Article
en En
| MEDLINE
| ID: mdl-26289448
ABSTRACT
OBJECTIVES:
To examine the effects of telephone-delivered lifestyle coaching on preventing the development of type 2 diabetes mellitus (T2DM) in participants with impaired fasting glucose (IFG).DESIGN:
Cluster randomised trial.SETTING:
40 groups from 17 healthcare divisions in Japan companies (31), communities (6) and mixed settings (3).PARTICIPANTS:
Participants aged 20-65 years with fasting plasma glucose (FPG) of 5.6-6.9 mmol/L were invited from the 17 healthcare divisions. RANDOMISATION The groups were then randomly assigned to an intervention or a control arm by independent statisticians according to a computer-generated list. INTERVENTION The intervention arm received a 1-year telephone-delivered intervention provided by three private lifestyle support centres (at different frequencies low-frequency (3 times), middle-frequency (6 times) and high-frequency (10 times) support calls). The intervention and control arms both received self-help devices such as a weight scale and pedometer.OUTCOMES:
Participants were followed up using data from annual health check-ups and a questionnaire regarding lifestyle. The primary outcome was the development of T2DM defined as FPG ≥ 7.0 mmol/L, the diagnosis of diabetes, or use of an antidiabetic drug, confirmed by referring to medical cards.RESULTS:
Of 14,473 screened individuals, participants were enrolled in either the intervention (n = 1240) arm or control (n = 1367) arm. Overall, the HR for the development of T2DM in the intervention arm during 5.5 years was 1.00 (95% CI 0.74 to 1.34). In the subanalysis, the HR was 0.59 (95% CI 0.42 to 0.83) in the subgroup that received phone calls the most frequently, compared with the control arm. A limitation of the study includes a lack of blinding.CONCLUSIONS:
High-frequency telephone-delivered lifestyle support could effectively prevent T2DM in participants with IFG in a primary healthcare setting, although low-frequency and middle-frequency phone calls did not. TRIAL REGISTRATION NUMBER This trial has been registered with the University Hospital Medical Information Network (UMIN000000662).Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Estado Prediabético
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Teléfono
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Conductas Relacionadas con la Salud
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Diabetes Mellitus Tipo 2
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Promoción de la Salud
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Servicios de Salud
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Estilo de Vida
Tipo de estudio:
Clinical_trials
/
Etiology_studies
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Risk_factors_studies
Límite:
Adult
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Female
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Humans
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Male
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Middle aged
País/Región como asunto:
Asia
Idioma:
En
Revista:
BMJ Open
Año:
2015
Tipo del documento:
Article
País de afiliación:
Japón