Role of genetic variation in docetaxel-induced neutropenia and pharmacokinetics.

Nieuweboer, A J M; Smid, M; de Graan, A-J M; Elbouazzaoui, S; de Bruijn, P; Eskens, F A L M; Hamberg, P; Martens, J W M; Sparreboom, A; de Wit, R; van Schaik, R H N; Mathijssen, R H J

Nieuweboer, A J M; Smid, M; de Graan, A-J M; Elbouazzaoui, S; de Bruijn, P; Eskens, F A L M; Hamberg, P; Martens, J W M; Sparreboom, A; de Wit, R; van Schaik, R H N; Mathijssen, R H J.

Afiliación

Nieuweboer AJ; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Smid M; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
de Graan AM; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Elbouazzaoui S; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.
de Bruijn P; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Eskens FA; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Hamberg P; Department of Internal Medicine, St. Franciscus Gasthuis, Rotterdam, The Netherlands.
Martens JW; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
Sparreboom A; Department of Pharmaceutical Sciences, St Jude Children's Research Hospital, Memphis, TN, USA.
de Wit R; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.
van Schaik RH; Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands.
Mathijssen RH; Department of Medical Oncology, Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, The Netherlands.

Pharmacogenomics J ; 16(6): 519-524, 2016 11.

Article en En | MEDLINE | ID: mdl-26345519

Asunto(s)

Antineoplásicos/efectos adversos; Antineoplásicos/farmacocinética; Neutropenia/genética; Variantes Farmacogenómicas; Polimorfismo de Nucleótido Simple; Taxoides/efectos adversos; Taxoides/farmacocinética; Adolescente; Adulto; Anciano; Anciano de 80 o más Años; Antineoplásicos/administración & dosificación; Bases de Datos Genéticas; Docetaxel; Femenino; Predisposición Genética a la Enfermedad; Humanos; Inactivación Metabólica/genética; Masculino; Proteínas de Transporte de Membrana/genética; Proteínas de Transporte de Membrana/metabolismo; Tasa de Depuración Metabólica/genética; Persona de Mediana Edad; Modelos Genéticos; Neutropenia/inducido químicamente; Farmacogenética; Fenotipo; Factores de Riesgo; Índice de Severidad de la Enfermedad; Taxoides/administración & dosificación; Adulto Joven

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Polimorfismo de Nucleótido Simple / Taxoides / Variantes Farmacogenómicas / Neutropenia / Antineoplásicos Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Pharmacogenomics J Asunto de la revista: BIOLOGIA MOLECULAR / FARMACOLOGIA Año: 2016 Tipo del documento: Article País de afiliación: Países Bajos

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