Clinical and pathologic diagnosis and different diagnosis of syphilis cervical lymphadenitis.
Int J Clin Exp Pathol
; 8(10): 13635-8, 2015.
Article
en En
| MEDLINE
| ID: mdl-26722588
ABSTRACT
PURPOSE:
To study the clinical pathologic characteristics and differential diagnosis of syphilitic cervical lymphadenitis, and to improve the rate of its diagnosis and treatment.METHODS:
Retrospectively analyzed the clinical history, Trepone pallidum-ELISA (TP-ELISA), rapid plasma regain test (RPR) and routine pathological examination of the patient diagnosed as syphilis lymphadenitis. And review related literatures.RESULTS:
The main clinical presentation was multiple palpable cervical lymph nodes. The multiple nodes were hard, fixed, and the major diameter of the larger one was 2 cm. The main pathological changes included the capsule was significantly thickened; reactive hyperplasia of lymphoid follicular with sky star phenomenon; occlusive endovasculitis; perivascular inflammation; the proliferation of epithelioid histiocytes can form granulomas with few multinucleated giant cells; few necrosis. TP-ELISA and RPR were positive.CONCLUSIONS:
The pathological changes of syphilitic lymphadenitis have a variety of performance with relatively specific and suggestive alterations which requires a combination of clinical history and laboratory test before the diagnosis, and the clinicians can reduce misdiagnosis and missed diagnosis of the disease by increasing vigilance of it.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Treponema pallidum
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Sífilis
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Linfadenitis
Tipo de estudio:
Diagnostic_studies
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Observational_studies
Límite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
Int J Clin Exp Pathol
Asunto de la revista:
PATOLOGIA
Año:
2015
Tipo del documento:
Article
País de afiliación:
China