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Discovery and characterization of Isofistularin-3, a marine brominated alkaloid, as a new DNA demethylating agent inducing cell cycle arrest and sensitization to TRAIL in cancer cells.
Florean, Cristina; Schnekenburger, Michael; Lee, Jin-Young; Kim, Kyung Rok; Mazumder, Aloran; Song, Sungmi; Kim, Jae-Myun; Grandjenette, Cindy; Kim, Jeoung-Gyun; Yoon, Ah-Young; Dicato, Mario; Kim, Kyu-Won; Christov, Christo; Han, Byung-Woo; Proksch, Peter; Diederich, Marc.
Afiliación
  • Florean C; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, Lëtzebuerg, Luxembourg.
  • Schnekenburger M; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, Lëtzebuerg, Luxembourg.
  • Lee JY; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
  • Kim KR; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
  • Mazumder A; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
  • Song S; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
  • Kim JM; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
  • Grandjenette C; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, Lëtzebuerg, Luxembourg.
  • Kim JG; SNU-Harvard Neurovascular Protection Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Gwanak-gu, Korea.
  • Yoon AY; SNU-Harvard Neurovascular Protection Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Gwanak-gu, Korea.
  • Dicato M; Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg, Lëtzebuerg, Luxembourg.
  • Kim KW; SNU-Harvard Neurovascular Protection Center, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Gwanak-gu, Korea.
  • Christov C; Faculté de Médecine, Université de Lorraine, Nancy, France.
  • Han BW; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
  • Proksch P; Institut für Pharmazeutische Biologie und Biotechnologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
  • Diederich M; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Gwanak-gu, Korea.
Oncotarget ; 7(17): 24027-49, 2016 Apr 26.
Article en En | MEDLINE | ID: mdl-27006469
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pez Cebra / Resistencia a Antineoplásicos / Metilación de ADN / Alcaloides / Ligando Inductor de Apoptosis Relacionado con TNF / Puntos de Control del Ciclo Celular / Neoplasias Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: Luxemburgo
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pez Cebra / Resistencia a Antineoplásicos / Metilación de ADN / Alcaloides / Ligando Inductor de Apoptosis Relacionado con TNF / Puntos de Control del Ciclo Celular / Neoplasias Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: Luxemburgo