Pegylated interferon therapy during early pregnancy for hepatitis B infection: does it prevent vertical transmission?
J Matern Fetal Neonatal Med
; 30(6): 745-747, 2017 Mar.
Article
en En
| MEDLINE
| ID: mdl-27125766
ABSTRACT
In general, interferon (IFN) is avoided during pregnancy due to the possibility of fetal side effects. We, herein, reported two child-bearing women with chronic hepatitis B (HB) infection who used pegylated interferon alfa 2b (PEG IFNα 2b) in first trimester unintentionally. We compared HB contracting rates of gestations in which IFN was used and not used. The cases are unique in that they could highlight the importance of IFN use in early gestation for preventing vertical transmission particularly if combined with antiviral therapy for the rest of pregnancy.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Antivirales
/
Polietilenglicoles
/
Complicaciones Infecciosas del Embarazo
/
Interferón-alfa
/
Vacunas contra Hepatitis B
/
Transmisión Vertical de Enfermedad Infecciosa
/
Hepatitis B
Límite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
Revista:
J Matern Fetal Neonatal Med
Asunto de la revista:
OBSTETRICIA
/
PERINATOLOGIA
Año:
2017
Tipo del documento:
Article
País de afiliación:
Turquía