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Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor.
Rothhammer, Veit; Mascanfroni, Ivan D; Bunse, Lukas; Takenaka, Maisa C; Kenison, Jessica E; Mayo, Lior; Chao, Chun-Cheih; Patel, Bonny; Yan, Raymond; Blain, Manon; Alvarez, Jorge I; Kébir, Hania; Anandasabapathy, Niroshana; Izquierdo, Guillermo; Jung, Steffen; Obholzer, Nikolaus; Pochet, Nathalie; Clish, Clary B; Prinz, Marco; Prat, Alexandre; Antel, Jack; Quintana, Francisco J.
Afiliación
  • Rothhammer V; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Mascanfroni ID; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Bunse L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Takenaka MC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Kenison JE; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Mayo L; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Chao CC; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Patel B; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Yan R; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Blain M; Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada.
  • Alvarez JI; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Kébir H; Neuroimmunology Research Lab, Center for Excellence in Neuromics CRCHUM, Université de Montréal, Montréal, Quebec, Canada.
  • Anandasabapathy N; Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
  • Izquierdo G; Molecular Biology Service, University of Sevilla, Sevilla, Spain.
  • Jung S; Department of Immunology, Weizmann Institute of Science, Rehovot, Israel.
  • Obholzer N; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Pochet N; Broad Institute of the Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, Massachusetts, USA.
  • Clish CB; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
  • Prinz M; Broad Institute of the Massachusetts Institute of Technology (MIT) and Harvard University, Cambridge, Massachusetts, USA.
  • Prat A; Metabolite Profiling Platform, Broad Institute of MIT and Harvard University, Cambridge, Massachusetts, USA.
  • Antel J; Institute of Neuropathology, University of Freiburg, Freiburg, Germany.
  • Quintana FJ; Neuroimmunology Research Lab, Center for Excellence in Neuromics CRCHUM, Université de Montréal, Montréal, Quebec, Canada.
Nat Med ; 22(6): 586-97, 2016 06.
Article en En | MEDLINE | ID: mdl-27158906
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Triptófano / Linfocitos T / Interferón Tipo I / Astrocitos / Receptores de Hidrocarburo de Aril / Encefalomielitis Autoinmune Experimental / Microbioma Gastrointestinal / Esclerosis Múltiple Tipo de estudio: Observational_studies Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Triptófano / Linfocitos T / Interferón Tipo I / Astrocitos / Receptores de Hidrocarburo de Aril / Encefalomielitis Autoinmune Experimental / Microbioma Gastrointestinal / Esclerosis Múltiple Tipo de estudio: Observational_studies Idioma: En Revista: Nat Med Asunto de la revista: BIOLOGIA MOLECULAR / MEDICINA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos