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Conjugation to the sigma-2 ligand SV119 overcomes uptake blockade and converts dm-Erastin into a potent pancreatic cancer therapeutic.
Ohman, Kerri A; Hashim, Yassar M; Vangveravong, Suwanna; Nywening, Timothy M; Cullinan, Darren R; Goedegebuure, S Peter; Liu, Jingxia; Van Tine, Brian A; Tiriac, Herve; Tuveson, David A; DeNardo, David G; Spitzer, Dirk; Mach, Robert H; Hawkins, William G.
Afiliación
  • Ohman KA; Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Hashim YM; Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Vangveravong S; Department of Radiology, Washington University School of Medicine, St. Louis, MO, USA.
  • Nywening TM; Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Cullinan DR; Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Goedegebuure SP; Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Liu J; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.
  • Van Tine BA; Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
  • Tiriac H; Division of Public Health Sciences, Section of Oncologic Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • Tuveson DA; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.
  • DeNardo DG; Division of Medical Oncology, Washington University School of Medicine, St. Louis, MO, USA.
  • Spitzer D; Cold Spring Harbor Laboratory, New York, NY, USA.
  • Mach RH; Cold Spring Harbor Laboratory, New York, NY, USA.
  • Hawkins WG; Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, and Washington University School of Medicine, St. Louis, MO, USA.
Oncotarget ; 7(23): 33529-41, 2016 Jun 07.
Article en En | MEDLINE | ID: mdl-27244881
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Piperazinas / Carbamatos / Sistemas de Liberación de Medicamentos / Compuestos de Azabiciclo / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Piperazinas / Carbamatos / Sistemas de Liberación de Medicamentos / Compuestos de Azabiciclo / Antineoplásicos Límite: Animals / Humans Idioma: En Revista: Oncotarget Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos