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A loss of function variant in CASP7 protects against Alzheimer's disease in homozygous APOE ε4 allele carriers.
Ayers, Kristin L; Mirshahi, Uyenlinh L; Wardeh, Amr H; Murray, Michael F; Hao, Ke; Glicksberg, Benjamin S; Li, Shuyu; Carey, David J; Chen, Rong.
Afiliación
  • Ayers KL; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Mirshahi UL; Geisinger Clinic, Danville, PA, 17822, USA.
  • Wardeh AH; Geisinger Clinic, Danville, PA, 17822, USA.
  • Murray MF; Geisinger Clinic, Danville, PA, 17822, USA.
  • Hao K; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Glicksberg BS; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Li S; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Carey DJ; Geisinger Clinic, Danville, PA, 17822, USA.
  • Chen R; Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. rong.chen@mssm.edu.
BMC Genomics ; 17 Suppl 2: 445, 2016 06 23.
Article en En | MEDLINE | ID: mdl-27358062
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Apolipoproteínas E / Análisis de Secuencia de ARN / Perfilación de la Expresión Génica / Caspasa 7 / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: BMC Genomics Asunto de la revista: GENETICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Apolipoproteínas E / Análisis de Secuencia de ARN / Perfilación de la Expresión Génica / Caspasa 7 / Enfermedad de Alzheimer Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Humans Idioma: En Revista: BMC Genomics Asunto de la revista: GENETICA Año: 2016 Tipo del documento: Article País de afiliación: Estados Unidos