EGFR gene amplification is relatively common and associates with outcome in intestinal adenocarcinoma of the stomach, gastro-oesophageal junction and distal oesophagus.

Birkman, Eva-Maria; Ålgars, Annika; Lintunen, Minnamaija; Ristamäki, Raija; Sundström, Jari; Carpén, Olli

Birkman, Eva-Maria; Ålgars, Annika; Lintunen, Minnamaija; Ristamäki, Raija; Sundström, Jari; Carpén, Olli.

Afiliación

Birkman EM; Department of Pathology, University of Turku and Turku University Hospital, TYKS-SAPA, Turku, Finland. emabir@utu.fi.
Ålgars A; Department of Oncology, University of Turku and Turku University Hospital, Turku, Finland.
Lintunen M; MediCity Research Laboratory, University of Turku, Turku, Finland.
Ristamäki R; Department of Pathology, University of Turku and Turku University Hospital, TYKS-SAPA, Turku, Finland.
Sundström J; Department of Oncology, University of Turku and Turku University Hospital, Turku, Finland.
Carpén O; Department of Pathology, University of Turku and Turku University Hospital, TYKS-SAPA, Turku, Finland.

BMC Cancer ; 16: 406, 2016 07 07.

Article en En | MEDLINE | ID: mdl-27387915

Asunto(s)

Receptores ErbB/genética; Neoplasias Esofágicas/genética; Amplificación de Genes; Neoplasias Intestinales/genética; Receptor ErbB-2/genética; Adulto; Anciano; Anciano de 80 o más Años; Receptores ErbB/metabolismo; Neoplasias Esofágicas/metabolismo; Unión Esofagogástrica/metabolismo; Unión Esofagogástrica/patología; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Neoplasias Intestinales/metabolismo; Neoplasias Intestinales/patología; Masculino; Persona de Mediana Edad; Pronóstico; Receptor ErbB-2/metabolismo; Análisis de Supervivencia

Palabras clave

EGFR; Gastric cancer; Gene amplification; HER2; Silver in situ hybridization

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias Esofágicas / Amplificación de Genes / Receptor ErbB-2 / Receptores ErbB / Neoplasias Intestinales Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: BMC Cancer Asunto de la revista: NEOPLASIAS Año: 2016 Tipo del documento: Article País de afiliación: Finlandia

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