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DNA polymerase ι functions in the generation of tandem mutations during somatic hypermutation of antibody genes.
Maul, Robert W; MacCarthy, Thomas; Frank, Ekaterina G; Donigan, Katherine A; McLenigan, Mary P; Yang, William; Saribasak, Huseyin; Huston, Donald E; Lange, Sabine S; Woodgate, Roger; Gearhart, Patricia J.
Afiliación
  • Maul RW; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224.
  • MacCarthy T; Department of Applied Mathematics and Statistics, State University of New York, Stony Brook, NY 11794.
  • Frank EG; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20850.
  • Donigan KA; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20850.
  • McLenigan MP; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20850.
  • Yang W; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224.
  • Saribasak H; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224.
  • Huston DE; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20850.
  • Lange SS; Department of Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center Science Park, Smithville, TX 78957.
  • Woodgate R; Laboratory of Genomic Integrity, National Institute of Child Health and Human Development, National Institutes of Health, Rockville, MD 20850.
  • Gearhart PJ; Laboratory of Molecular Biology and Immunology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224 gearhartp@mail.nih.gov.
J Exp Med ; 213(9): 1675-83, 2016 08 22.
Article en En | MEDLINE | ID: mdl-27455952

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Genes de Inmunoglobulinas / Hipermutación Somática de Inmunoglobulina / ADN Polimerasa Dirigida por ADN Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Exp Med Año: 2016 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Genes de Inmunoglobulinas / Hipermutación Somática de Inmunoglobulina / ADN Polimerasa Dirigida por ADN Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Exp Med Año: 2016 Tipo del documento: Article