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THPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteria.
Cox, Jonathan A G; Abrahams, Katherine A; Alemparte, Carlos; Ghidelli-Disse, Sonja; Rullas, Joaquín; Angulo-Barturen, Iñigo; Singh, Albel; Gurcha, Sudagar S; Nataraj, Vijayashankar; Bethell, Stephen; Remuiñán, Modesto J; Encinas, Lourdes; Jervis, Peter J; Cammack, Nicholas C; Bhatt, Apoorva; Kruse, Ulrich; Bantscheff, Marcus; Fütterer, Klaus; Barros, David; Ballell, Lluis; Drewes, Gerard; Besra, Gurdyal S.
Afiliación
  • Cox JA; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Abrahams KA; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Alemparte C; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Ghidelli-Disse S; Cellzome, Meyerhofstrasse 1, Heidelberg 69117, Germany.
  • Rullas J; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Angulo-Barturen I; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Singh A; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Gurcha SS; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Nataraj V; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Bethell S; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Remuiñán MJ; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Encinas L; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Jervis PJ; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Cammack NC; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Bhatt A; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Kruse U; Cellzome, Meyerhofstrasse 1, Heidelberg 69117, Germany.
  • Bantscheff M; Cellzome, Meyerhofstrasse 1, Heidelberg 69117, Germany.
  • Fütterer K; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
  • Barros D; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Ballell L; Diseases of the Developing World, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos, Madrid 28760, Spain.
  • Drewes G; Cellzome, Meyerhofstrasse 1, Heidelberg 69117, Germany.
  • Besra GS; Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Nat Microbiol ; 1: 15006, 2016 Jan 18.
Article en En | MEDLINE | ID: mdl-27571973
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Proteínas Bacterianas / Ácidos Grasos Esenciales / Genes Esenciales / Proteínas de Unión a Ácidos Grasos / Mycobacterium tuberculosis / Antituberculosos Límite: Animals Idioma: En Revista: Nat Microbiol Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirazoles / Pirimidinas / Proteínas Bacterianas / Ácidos Grasos Esenciales / Genes Esenciales / Proteínas de Unión a Ácidos Grasos / Mycobacterium tuberculosis / Antituberculosos Límite: Animals Idioma: En Revista: Nat Microbiol Año: 2016 Tipo del documento: Article País de afiliación: Reino Unido