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HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1ß production via suppressing the NF-κB pathway and ROS production.
Yu, Xin; Lan, Peixiang; Hou, Xuben; Han, Qiuju; Lu, Nan; Li, Tao; Jiao, Chenwei; Zhang, Jian; Zhang, Cai; Tian, Zhigang.
Afiliación
  • Yu X; Institute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China.
  • Lan P; Institute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China.
  • Hou X; Department of Medicinal Chemistry, Key Laboratory of Chemical Biology of Natural Products (MOE), School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China.
  • Han Q; Institute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China.
  • Lu N; Institute of Diagnostics, School of Medicine, Shandong University, Jinan 250012, Shandong, China.
  • Li T; Division of Liver Diseases, Shandong Provincial Hospital, Jinan 250001, Shandong, China.
  • Jiao C; Department of Pediatric Surgery, Shandong Provincial Hospital, Jinan 250001, Shandong, China.
  • Zhang J; Institute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China.
  • Zhang C; Institute of Immunopharmacology and Immunotherapy, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, Shandong, China. Electronic address: caizhangsd@sdu.edu.cn.
  • Tian Z; Institute of Immunology, School of Life Sciences, University of Science and Technology of China, Hefei 230027, Anhui, China. Electronic address: tzg@ustc.edu.cn.
J Hepatol ; 66(4): 693-702, 2017 04.
Article en En | MEDLINE | ID: mdl-28027970
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / FN-kappa B / Interleucina-1beta / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Virus de la Hepatitis B / FN-kappa B / Interleucina-1beta / Inflamasomas / Proteína con Dominio Pirina 3 de la Familia NLR Tipo de estudio: Etiology_studies / Prognostic_studies Límite: Animals / Humans / Male Idioma: En Revista: J Hepatol Asunto de la revista: GASTROENTEROLOGIA Año: 2017 Tipo del documento: Article País de afiliación: China