Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)<sub>n</sub> and (X)<sub>n</sub>K/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics.

Tsiatsiani, Liana; Giansanti, Piero; Scheltema, Richard A; van den Toorn, Henk; Overall, Christopher M; Altelaar, A F Maarten; Heck, Albert J R

Opposite Electron-Transfer Dissociation and Higher-Energy Collisional Dissociation Fragmentation Characteristics of Proteolytic K/R(X)_n and (X)_nK/R Peptides Provide Benefits for Peptide Sequencing in Proteomics and Phosphoproteomics.

Tsiatsiani, Liana; Giansanti, Piero; Scheltema, Richard A; van den Toorn, Henk; Overall, Christopher M; Altelaar, A F Maarten; Heck, Albert J R.

Afiliación

Overall CM; Centre for Blood Research, Department of Oral Biological and Medical Sciences, and Department of Biochemistry and Molecular Biology, University of British Columbia , Vancouver V6T 1Z3, BC, Canada.

J Proteome Res ; 16(2): 852-861, 2017 02 03.

Article en En | MEDLINE | ID: mdl-28111955

Asunto(s)

Electrones; Metaloproteasas/química; Fragmentos de Péptidos/análisis; Fosfoproteínas/química; Protones; Tripsina/química; Secuencia de Aminoácidos; Sitios de Unión; Cinética; Unión Proteica; Conformación Proteica en Hélice alfa; Conformación Proteica en Lámina beta; Dominios Proteicos; Proteolisis; Proteómica/métodos; Análisis de Secuencia de Proteína; Termodinámica

Palabras clave

LysargiNase; electron-transfer dissociation; higher-energy collisional dissociation; peptide fragmentation; phosphoproteomics; proteomics; trypsin

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fragmentos de Péptidos / Fosfoproteínas / Protones / Tripsina / Metaloproteasas / Electrones Tipo de estudio: Prognostic_studies Idioma: En Revista: J Proteome Res Asunto de la revista: BIOQUIMICA Año: 2017 Tipo del documento: Article

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