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Momelotinib inhibits ACVR1/ALK2, decreases hepcidin production, and ameliorates anemia of chronic disease in rodents.
Asshoff, Malte; Petzer, Verena; Warr, Matthew R; Haschka, David; Tymoszuk, Piotr; Demetz, Egon; Seifert, Markus; Posch, Wilfried; Nairz, Manfred; Maciejewski, Pat; Fowles, Peter; Burns, Christopher J; Smith, Gregg; Wagner, Kay-Uwe; Weiss, Guenter; Whitney, J Andrew; Theurl, Igor.
Afiliación
  • Asshoff M; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Petzer V; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Warr MR; Department of Biology, Gilead Sciences, Inc., Foster City, CA.
  • Haschka D; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Tymoszuk P; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Demetz E; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Seifert M; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Posch W; Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
  • Nairz M; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Maciejewski P; Department of Biology, Gilead Sciences, Inc., Foster City, CA.
  • Fowles P; Department of Biology, Gilead Sciences, Inc., Foster City, CA.
  • Burns CJ; Department of Biology, Gilead Sciences, Inc., Foster City, CA.
  • Smith G; The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia; and.
  • Wagner KU; Department of Biology, Gilead Sciences, Inc., Foster City, CA.
  • Weiss G; Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE.
  • Whitney JA; Department of Internal Medicine VI (Infectious Diseases, Immunology, Rheumatology and Pneumology), Medical University of Innsbruck, Innsbruck, Austria.
  • Theurl I; Department of Biology, Gilead Sciences, Inc., Foster City, CA.
Blood ; 129(13): 1823-1830, 2017 03 30.
Article en En | MEDLINE | ID: mdl-28188131
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Benzamidas / Receptores de Proteínas Morfogenéticas Óseas de Tipo 1 / Hepcidinas / Anemia Límite: Animals Idioma: En Revista: Blood Año: 2017 Tipo del documento: Article País de afiliación: Austria
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Pirimidinas / Benzamidas / Receptores de Proteínas Morfogenéticas Óseas de Tipo 1 / Hepcidinas / Anemia Límite: Animals Idioma: En Revista: Blood Año: 2017 Tipo del documento: Article País de afiliación: Austria