Early-onset neonatal sepsis is associated with a high heart rate during automatically selected stationary periods.
Acta Paediatr
; 106(5): 749-754, 2017 May.
Article
en En
| MEDLINE
| ID: mdl-28196284
ABSTRACT
AIM:
This study examined the heart rate variability characteristics associated with early-onset neonatal sepsis in a prospective, observational controlled study.METHODS:
Eligible patients were full-term neonates hospitalised with clinical signs that suggested early-onset sepsis and a C-reactive protein of >10 mg/L. Sepsis was considered proven in cases of symptomatic septicaemia, meningitis, pneumonia or enterocolitis. Heart rate variability parameters (n = 16) were assessed from five-, 15- and 30-minute stationary sequences automatically selected from electrocardiographic recordings performed at admission and compared with a control group using the U-test with post hoc Benjamini-Yekutieli correction. Stationary sequences corresponded to the periods with the lowest changes of heart rate variability over time.RESULTS:
A total of 40 full-term infants were enrolled, including 14 with proven sepsis. The mean duration of the cardiac cycle length was lower in the proven sepsis group than in the control group (n = 11), without other significant changes in heart rate variability parameters. These durations, measured in five-minute stationary periods, were 406 (367-433) ms in proven sepsis group versus 507 (463-522) ms in the control group (p < 0.05).CONCLUSION:
Early-onset neonatal sepsis was associated with a high mean heart rate measured during automatically selected stationary periods.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Sepsis Neonatal
/
Frecuencia Cardíaca
Tipo de estudio:
Observational_studies
/
Risk_factors_studies
Límite:
Female
/
Humans
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Male
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Newborn
Idioma:
En
Revista:
Acta Paediatr
Año:
2017
Tipo del documento:
Article
País de afiliación:
Francia