Phloretin exerts hypoglycemic effect in streptozotocin-induced diabetic rats and improves insulin resistance in vitro.

Shen, Xin; Zhou, Nan; Mi, Le; Hu, Zishuo; Wang, Libin; Liu, Xueying; Zhang, Shengyong

Shen, Xin; Zhou, Nan; Mi, Le; Hu, Zishuo; Wang, Libin; Liu, Xueying; Zhang, Shengyong.

Afiliación

Shen X; Department of Medicinal Chemistry, School of Pharmacy.
Zhou N; Department of Medicinal Chemistry, School of Pharmacy.
Mi L; Department of Medicinal Chemistry, School of Pharmacy.
Hu Z; Student Brigade, The Fourth Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Wang L; Department of Medicinal Chemistry, School of Pharmacy.
Liu X; Department of Medicinal Chemistry, School of Pharmacy.
Zhang S; Department of Medicinal Chemistry, School of Pharmacy.

Drug Des Devel Ther ; 11: 313-324, 2017.

Article en En | MEDLINE | ID: mdl-28223777

Asunto(s)

Diabetes Mellitus Experimental/tratamiento farmacológico; Hipoglucemiantes/uso terapéutico; Resistencia a la Insulina; Floretina/uso terapéutico; Animales; Glucemia/análisis; Supervivencia Celular; Células Cultivadas; Diabetes Mellitus Experimental/inducido químicamente; Diabetes Mellitus Experimental/patología; Glucosa/administración & dosificación; Glucosa/metabolismo; Prueba de Tolerancia a la Glucosa; Masculino; Estructura Molecular; Floretina/administración & dosificación; Ratas; Ratas Sprague-Dawley; Estreptozocina

Palabras clave

blood glucose consumption; diabetes; insulin sensitivity; phloretin; skeletal muscle

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Floretina / Resistencia a la Insulina / Diabetes Mellitus Experimental / Hipoglucemiantes Límite: Animals Idioma: En Revista: Drug Des Devel Ther Asunto de la revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Año: 2017 Tipo del documento: Article

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