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Deletion of ribosomal protein genes is a common vulnerability in human cancer, especially in concert with TP53 mutations.
Ajore, Ram; Raiser, David; McConkey, Marie; Jöud, Magnus; Boidol, Bernd; Mar, Brenton; Saksena, Gordon; Weinstock, David M; Armstrong, Scott; Ellis, Steven R; Ebert, Benjamin L; Nilsson, Björn.
Afiliación
  • Ajore R; Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden.
  • Raiser D; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • McConkey M; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Jöud M; Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden.
  • Boidol B; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Mar B; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
  • Saksena G; Broad Institute, 7 Cambridge Center, Cambridge, MA, USA.
  • Weinstock DM; Dana-Farber Cancer Institute, Boston, MA, USA.
  • Armstrong S; Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Ellis SR; Department of Biochemistry and Molecular Biology, University of Louisville, Louisville, KY, USA.
  • Ebert BL; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA benjamin_ebert@dfci.harvard.edu bjorn.nilsson@med.lu.se.
  • Nilsson B; Broad Institute, 7 Cambridge Center, Cambridge, MA, USA.
EMBO Mol Med ; 9(4): 498-507, 2017 04.
Article en En | MEDLINE | ID: mdl-28264936
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Ribosómicas / Proteína p53 Supresora de Tumor / Eliminación de Gen / Mutación / Neoplasias Límite: Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: Suecia
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Proteínas Ribosómicas / Proteína p53 Supresora de Tumor / Eliminación de Gen / Mutación / Neoplasias Límite: Humans Idioma: En Revista: EMBO Mol Med Asunto de la revista: BIOLOGIA MOLECULAR Año: 2017 Tipo del documento: Article País de afiliación: Suecia