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Codon-level co-occurrences of germline variants and somatic mutations in cancer are rare but often lead to incorrect variant annotation and underestimated impact prediction.
Koire, Amanda; Kim, Young Won; Wang, Jarey; Katsonis, Panagiotis; Jin, Haijing; Lichtarge, Olivier.
Afiliación
  • Koire A; Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America.
  • Kim YW; Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas, United States of America.
  • Wang J; Program in Integrative Molecular and Biomedical Sciences, Baylor College of Medicine, Houston, Texas, United States of America.
  • Katsonis P; Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas, United States of America.
  • Jin H; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas, United States of America.
  • Lichtarge O; Program in Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, Texas, United States of America.
PLoS One ; 12(3): e0174766, 2017.
Article en En | MEDLINE | ID: mdl-28350864
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Codón / Mutación de Línea Germinal / Mutación / Neoplasias Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Codón / Mutación de Línea Germinal / Mutación / Neoplasias Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Female / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos