The 150-Loop Restricts the Host Specificity of Human H10N8 Influenza Virus.

Tzarum, Netanel; de Vries, Robert P; Peng, Wenjie; Thompson, Andrew J; Bouwman, Kim M; McBride, Ryan; Yu, Wenli; Zhu, Xueyong; Verheije, Monique H; Paulson, James C; Wilson, Ian A

Tzarum, Netanel; de Vries, Robert P; Peng, Wenjie; Thompson, Andrew J; Bouwman, Kim M; McBride, Ryan; Yu, Wenli; Zhu, Xueyong; Verheije, Monique H; Paulson, James C; Wilson, Ian A.

Afiliación

Tzarum N; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
de Vries RP; Department of Molecular Medicine and Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CG Utrech
Peng W; Department of Molecular Medicine and Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Thompson AJ; Department of Molecular Medicine and Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Bouwman KM; Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, the Netherlands.
McBride R; Department of Molecular Medicine and Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Yu W; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Zhu X; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.
Verheije MH; Pathology Division, Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, the Netherlands.
Paulson JC; Department of Molecular Medicine and Department of Immunology and Microbiology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: jpaulson@scripps.edu.
Wilson IA; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA; Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. Electronic address: w

Cell Rep ; 19(2): 235-245, 2017 04 11.

Article en En | MEDLINE | ID: mdl-28402848

Asunto(s)

Hemaglutininas/química; Subtipo H10N8 del Virus de la Influenza A/genética; Gripe Aviar/virología; Gripe Humana/virología; Animales; Sitios de Unión; Aves; Cristalografía por Rayos X; Hemaglutininas/genética; Humanos; Subtipo H10N8 del Virus de la Influenza A/química; Subtipo H10N8 del Virus de la Influenza A/patogenicidad; Gripe Aviar/genética; Gripe Humana/genética; Proteínas Mutantes/química; Proteínas Mutantes/genética; Pandemias; Conformación Proteica

Palabras clave

150-loop; H10N8; HA; crystal structure; glycan array; hemagglutinin; host specificity; influenza A virus

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Gripe Humana / Subtipo H10N8 del Virus de la Influenza A / Gripe Aviar / Hemaglutininas Límite: Animals / Humans Idioma: En Revista: Cell Rep Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos

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