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Icariin protects against glucocorticoid induced osteoporosis, increases the expression of the bone enhancer DEC1 and modulates the PI3K/Akt/GSK3ß/ß-catenin integrated signaling pathway.
Hu, Jinhua; Mao, Zhao; He, Shuangcheng; Zhan, Yuanran; Ning, Rui; Liu, Wei; Yan, Bingfang; Yang, Jian.
Afiliación
  • Hu J; Pharmaceutical Preparation Section, Changzhou No. 7 People's Hospital, Changzhou 213000, China.
  • Mao Z; Jinling Hospital, Nanjing Medical University, Nanjing 210029, China.
  • He S; Department of Pharmacology, Nanjing Medical University, Nanjing 210029, China.
  • Zhan Y; Department of Pharmacology, Nanjing Medical University, Nanjing 210029, China.
  • Ning R; Department of Pharmacology, Nanjing Medical University, Nanjing 210029, China.
  • Liu W; Department of Pharmacology, Nanjing Medical University, Nanjing 210029, China.
  • Yan B; University of Rhode Island, Kingston, RI, USA.
  • Yang J; Department of Pharmacology, Nanjing Medical University, Nanjing 210029, China. Electronic address: jianyang@njmu.edu.cn.
Biochem Pharmacol ; 136: 109-121, 2017 07 15.
Article en En | MEDLINE | ID: mdl-28408345
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoporosis / Flavonoides / Fosfatidilinositol 3-Quinasas / Proteínas Supresoras de Tumor / Beta Catenina / Glucógeno Sintasa Quinasa 3 beta Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Osteoporosis / Flavonoides / Fosfatidilinositol 3-Quinasas / Proteínas Supresoras de Tumor / Beta Catenina / Glucógeno Sintasa Quinasa 3 beta Límite: Animals / Humans / Male Idioma: En Revista: Biochem Pharmacol Año: 2017 Tipo del documento: Article País de afiliación: China