A UPLC-MS/MS method for quantification of 5&#945;-androst-3ß,5,6ß-triol in human plasma: development, validation and its application in clinical pharmacokinetic study.

Wang, Zhenlei; Wang, Huanhuan; Hu, Pei; Jiang, Ji; Zhao, Qian

A UPLC-MS/MS method for quantification of 5α-androst-3ß,5,6ß-triol in human plasma: development, validation and its application in clinical pharmacokinetic study.

Wang, Zhenlei; Wang, Huanhuan; Hu, Pei; Jiang, Ji; Zhao, Qian.

Afiliación

Wang Z; Phase I Unit, Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100032, China.
Wang H; Phase I Unit, Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100032, China.
Hu P; Phase I Unit, Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100032, China.
Jiang J; Phase I Unit, Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100032, China.
Zhao Q; Phase I Unit, Clinical Pharmacology Research Center, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100032, China.

Bioanalysis ; 9(11): 873-885, 2017 Jun.

Article en En | MEDLINE | ID: mdl-28617033

Asunto(s)

Androstanoles/sangre; Cromatografía Líquida de Alta Presión/métodos; Espectrometría de Masas en Tándem/métodos; Humanos; Límite de Detección; Reproducibilidad de los Resultados; Extracción en Fase Sólida/métodos; Espectrometría de Masa por Ionización de Electrospray/métodos

Palabras clave

5α-androst-3ß,5,6ß-triol; UPLCMS/MS; human plasma; ischemic stroke

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Cromatografía Líquida de Alta Presión / Espectrometría de Masas en Tándem / Androstanoles Tipo de estudio: Guideline Límite: Humans Idioma: En Revista: Bioanalysis Año: 2017 Tipo del documento: Article País de afiliación: China

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