Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice.

Miyake, Masato; Kuroda, Masashi; Kiyonari, Hiroshi; Takehana, Kenji; Hisanaga, Satoshi; Morimoto, Masatoshi; Zhang, Jun; Oyadomari, Miho; Sakaue, Hiroshi; Oyadomari, Seiichi

Miyake, Masato; Kuroda, Masashi; Kiyonari, Hiroshi; Takehana, Kenji; Hisanaga, Satoshi; Morimoto, Masatoshi; Zhang, Jun; Oyadomari, Miho; Sakaue, Hiroshi; Oyadomari, Seiichi.

Afiliación

Miyake M; Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.
Kuroda M; Department of Molecular Research, Diabetes Therapeutics and Research Center, Tokushima University, Tokushima, Japan.
Kiyonari H; Fujii Memorial Institute of Medical Sciences, Tokushima University, Tokushima, Japan.
Takehana K; Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Hisanaga S; Animal Resource Development Unit and Genetic Engineering Team, RIKEN Center for Life Science Technologies, Kobe, Japan.
Morimoto M; Department of R&D planning, EA Pharma Co.,Ltd., Tokyo, Japan.
Zhang J; Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.
Oyadomari M; Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.
Sakaue H; Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan.
Oyadomari S; Department of Molecular Research, Diabetes Therapeutics and Research Center, Tokushima University, Tokushima, Japan.

PLoS One ; 12(6): e0179955, 2017.

Article en En | MEDLINE | ID: mdl-28644884

Asunto(s)

Modelos Animales de Enfermedad; Ratones Transgénicos; Músculo Esquelético; Atrofia Muscular; Actinas/genética; Actinas/metabolismo; Aminoácidos/metabolismo; Animales; Homeostasis/fisiología; Humanos; Espacio Intracelular/metabolismo; Ligandos; Diana Mecanicista del Complejo 1 de la Rapamicina; Ratones Endogámicos C57BL; Complejos Multiproteicos/metabolismo; Músculo Esquelético/metabolismo; Atrofia Muscular/metabolismo; Atrofia Muscular/patología; Regiones Promotoras Genéticas; Proteínas Serina-Treonina Quinasas/metabolismo; Serina-Treonina Quinasas TOR/metabolismo; Tacrolimus/análogos & derivados; eIF-2 Quinasa/genética; eIF-2 Quinasa/metabolismo

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Ratones Transgénicos / Atrofia Muscular / Músculo Esquelético / Modelos Animales de Enfermedad Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2017 Tipo del documento: Article País de afiliación: Japón

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