Revisiting the Structure of Hemoglobin and Myoglobin with Cryo-Electron Microscopy.
J Mol Biol
; 429(17): 2611-2618, 2017 08 18.
Article
en En
| MEDLINE
| ID: mdl-28697886
ABSTRACT
Sixty years ago, the first protein structure of myoglobin was determined by John Kendrew and his colleagues; hemoglobin followed shortly thereafter. For quite some time, it seemed that only X-ray crystallography would be capable of determining the structure of proteins to high resolution. In recent years, cryo-electron microscopy has emerged as a viable alternative and indeed in many cases the preferred approach. It is capable of studying proteins that span a size range from several megadaltons to proteins as small as myoglobin and hemoglobin.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Hemoglobinas
/
Microscopía por Crioelectrón
/
Mioglobina
Idioma:
En
Revista:
J Mol Biol
Año:
2017
Tipo del documento:
Article
País de afiliación:
Alemania