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Therapeutic antibody targeting of Notch3 signaling prevents mural cell loss in CADASIL.
Machuca-Parra, Arturo I; Bigger-Allen, Alexander A; Sanchez, Angie V; Boutabla, Anissa; Cardona-Vélez, Jonathan; Amarnani, Dhanesh; Saint-Geniez, Magali; Siebel, Christian W; Kim, Leo A; D'Amore, Patricia A; Arboleda-Velasquez, Joseph F.
Afiliación
  • Machuca-Parra AI; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • Bigger-Allen AA; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • Sanchez AV; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • Boutabla A; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • Cardona-Vélez J; Grenoble Alpes University, Grenoble, France.
  • Amarnani D; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • Saint-Geniez M; Universidad Pontificia Bolivariana, Medellín, Colombia.
  • Siebel CW; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • Kim LA; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
  • D'Amore PA; Department of Discovery Oncology, Genentech, Inc., South San Francisco, CA.
  • Arboleda-Velasquez JF; Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA.
J Exp Med ; 214(8): 2271-2282, 2017 Aug 07.
Article en En | MEDLINE | ID: mdl-28698285

Texto completo: 1 Base de datos: MEDLINE Asunto principal: CADASIL / Receptor Notch3 / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Exp Med Año: 2017 Tipo del documento: Article País de afiliación: Marruecos

Texto completo: 1 Base de datos: MEDLINE Asunto principal: CADASIL / Receptor Notch3 / Anticuerpos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Exp Med Año: 2017 Tipo del documento: Article País de afiliación: Marruecos