Primary Sjögren's syndrome and pregnancy: A report of 18 cases. / Síndrome de Sjögren primario y embarazo: reporte de 18 casos.
Reumatol Clin (Engl Ed)
; 15(2): 109-112, 2019.
Article
en En, Es
| MEDLINE
| ID: mdl-28844688
ABSTRACT
Primary Sjögren's syndrome (pSS) is a condition that predominantly affects women. Reports of pregnancy outcome in these patients are limited and contradictory. OBJECTIVE:
To describe pregnancy characteristics and outcomes and newborn morbidity in women with pSS. MATERIAL ANDMETHODS:
We included women with pSS who became pregnant after the onset of the symptoms of the disease. Clinical and serological characteristics, risk factors and previous maternal comorbidities are described. For each pregnancy in a woman with pSS, we recorded pregnancy course and outcome and newborn condition.RESULTS:
We assessed 11 patients with 18 pregnancies after the onset of pSS symptoms. All of them presented FAN +; 10 anti-Ro / SSA + and 7 anti-La / SSB +. The mean age in years at the onset of symptoms was 24.9 (SD 6.9) and at the time of pregnancy was 30.3 (SD 5.4). Thirteen pregnancies happened before the diagnosis, reporting only one miscarriage. Two preterm births, 1 case of oligohydramnios, 2 of premature membrane rupture and 2 low birthweight babies were reported after the onset of pSS symptoms. There was 1 newborn with congenital atrioventricular block and another with neonatal cutaneous lupus. All the women with pregnancy complications (n=6) had anti-Ro/SSA antibodies.CONCLUSIONS:
Almost half of the pregnancies assessed in women with pSS were associated with complications not attributable to factors other than the disease.Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Complicaciones del Embarazo
/
Síndrome de Sjögren
Tipo de estudio:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Female
/
Humans
/
Newborn
/
Pregnancy
Idioma:
En
/
Es
Revista:
Reumatol Clin (Engl Ed)
Año:
2019
Tipo del documento:
Article