Hox genes reveal genomic DNA variation in tetraploid hybrids derived from Carassius auratus red var. (female) × Megalobrama amblycephala (male).
BMC Genet
; 18(1): 86, 2017 10 11.
Article
en En
| MEDLINE
| ID: mdl-29020918
ABSTRACT
BACKGROUND:
Allotetraploid F1 hybrids (4nF1) (AABB, 4n = 148) were generated from the distant hybridization of Carassius auratus red var. (RCC) (AA, 2n = 100) (â) × Megalobrama amblycephala (BSB) (BB, 2n = 48) (â). It has been reported that Hox gene clusters are highly conserved among plants and vertebrates. In this study, we investigated the genomic organization of Hox gene clusters in the allotetraploid F1 hybrids and their parents to investigate the polyploidization process.RESULTS:
There were three copies of Hox genes in the 4nF1 hybrids, two copies in RCC and one copy in BSB. In addition, obvious variation and pseudogenization were observed in some Hox genes from 4nF1.CONCLUSION:
Our results reveal the influence of polyploidization on the organization and evolution of Hox gene clusters in fish and also clarify some aspects of vertebrate genome evolution.Palabras clave
Texto completo:
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Base de datos:
MEDLINE
Asunto principal:
Variación Genética
/
Carpa Dorada
/
Genes Homeobox
/
Tetraploidía
Límite:
Animals
Idioma:
En
Revista:
BMC Genet
Asunto de la revista:
BIOLOGIA MOLECULAR
/
BIOTECNOLOGIA
Año:
2017
Tipo del documento:
Article