Eppur Si Muove: ferritin is essential in modulating inflammation.
Clin Exp Immunol
; 191(2): 149-150, 2018 02.
Article
en En
| MEDLINE
| ID: mdl-29023673
ABSTRACT
Ferritin, which was only discovered in the last century, has stirred a formidable debate. Ferritin has long been appreciated as a non-specific acute-phase reactant. Several years ago, we hypothesized the contributory role of ferritin as a pathogenic molecule rather than being a product of inflammation. The latest emerging evidence provides support to this notion. Such revelation provides a step forward towards the understanding of disease conditions associated with hyperferritinaemia, and hence provide new targets for treatment modalities.
Palabras clave
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Proteínas de Fase Aguda
/
Trastornos del Metabolismo del Hierro
/
Ferritinas
/
Inflamación
/
Macrófagos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Clin Exp Immunol
Año:
2018
Tipo del documento:
Article
País de afiliación:
Israel