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Engineering improved variants of the antifungal peptide histatin 5 with reduced susceptibility to Candida albicans secreted aspartic proteases and enhanced antimicrobial potency.
Ikonomova, Svetlana P; Moghaddam-Taaheri, Parisa; Jabra-Rizk, Mary Ann; Wang, Yan; Karlsson, Amy J.
Afiliación
  • Ikonomova SP; Department of Chemical and Biomolecular Engineering, University of Maryland, College Park, MD, USA.
  • Moghaddam-Taaheri P; Fischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
  • Jabra-Rizk MA; Department of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, MD, USA.
  • Wang Y; Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, MD, USA.
  • Karlsson AJ; Proteomics Core Facility, College of Mathematics and Natural Sciences, University of Maryland, College Park, MD, USA.
FEBS J ; 285(1): 146-159, 2018 01.
Article en En | MEDLINE | ID: mdl-29143452
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Candida albicans / Proteínas Fúngicas / Péptidos Catiónicos Antimicrobianos / Histatinas / Proteasas de Ácido Aspártico / Antifúngicos Límite: Humans Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Candida albicans / Proteínas Fúngicas / Péptidos Catiónicos Antimicrobianos / Histatinas / Proteasas de Ácido Aspártico / Antifúngicos Límite: Humans Idioma: En Revista: FEBS J Asunto de la revista: BIOQUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Estados Unidos