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Overcoming resistance to single-agent therapy for oncogenic BRAF gene fusions via combinatorial targeting of MAPK and PI3K/mTOR signaling pathways.
Jain, Payal; Silva, Amanda; Han, Harry J; Lang, Shih-Shan; Zhu, Yuankun; Boucher, Katie; Smith, Tiffany E; Vakil, Aesha; Diviney, Patrick; Choudhari, Namrata; Raman, Pichai; Busch, Christine M; Delaney, Tim; Yang, Xiaodong; Olow, Aleksandra K; Mueller, Sabine; Haas-Kogan, Daphne; Fox, Elizabeth; Storm, Phillip B; Resnick, Adam C; Waanders, Angela J.
Afiliación
  • Jain P; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Silva A; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Han HJ; Center for Data Driven Discovery in Biomedicine (D3b), The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Lang SS; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Zhu Y; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Boucher K; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Smith TE; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Vakil A; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Diviney P; Center for Data Driven Discovery in Biomedicine (D3b), The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Choudhari N; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Raman P; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Busch CM; Center for Data Driven Discovery in Biomedicine (D3b), The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Delaney T; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Yang X; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Olow AK; Center for Data Driven Discovery in Biomedicine (D3b), The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Mueller S; The Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
  • Haas-Kogan D; Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Fox E; Division of Neurosurgery, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Storm PB; Department of Neurosurgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
  • Resnick AC; Center for Data Driven Discovery in Biomedicine (D3b), The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
  • Waanders AJ; Center for Data Driven Discovery in Biomedicine (D3b), The Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Oncotarget ; 8(49): 84697-84713, 2017 Oct 17.
Article en En | MEDLINE | ID: mdl-29156677
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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Oncotarget Año: 2017 Tipo del documento: Article País de afiliación: Estados Unidos