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Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.
Martin, Lesley-Ann; Ribas, Ricardo; Simigdala, Nikiana; Schuster, Eugene; Pancholi, Sunil; Tenev, Tencho; Gellert, Pascal; Buluwela, Laki; Harrod, Alison; Thornhill, Allan; Nikitorowicz-Buniak, Joanna; Bhamra, Amandeep; Turgeon, Marc-Olivier; Poulogiannis, George; Gao, Qiong; Martins, Vera; Hills, Margaret; Garcia-Murillas, Isaac; Fribbens, Charlotte; Patani, Neill; Li, Zheqi; Sikora, Matthew J; Turner, Nicholas; Zwart, Wilbert; Oesterreich, Steffi; Carroll, Jason; Ali, Simak; Dowsett, Mitch.
Afiliación
  • Martin LA; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK. Lesley-ann.martin@icr.ac.uk.
  • Ribas R; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Simigdala N; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Schuster E; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Pancholi S; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Tenev T; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Gellert P; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Buluwela L; Division of Cancer, CRUK Labs, University of London Imperial College, London, W12 0NN, UK.
  • Harrod A; Division of Cancer, CRUK Labs, University of London Imperial College, London, W12 0NN, UK.
  • Thornhill A; Centre for Cancer Imaging, Institute of Cancer Research, Sutton, SM2 5NG, UK.
  • Nikitorowicz-Buniak J; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Bhamra A; Proteomic Unit, Institute of Cancer Research, London, SW7 3RP, UK.
  • Turgeon MO; Division of Cancer Biology, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Poulogiannis G; Division of Cancer Biology, The Institute of Cancer Research, London, SW3 6JB, UK.
  • Gao Q; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, SW7 2AZ, UK.
  • Martins V; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Hills M; Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital, London, SW3 6JB, UK.
  • Garcia-Murillas I; Ralph Lauren Centre for Breast Cancer Research, Royal Marsden Hospital, London, SW3 6JB, UK.
  • Fribbens C; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Patani N; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Li Z; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Sikora MJ; Department of Pharmacology and Chemical biology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
  • Turner N; Department of Pharmacology and Chemical biology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
  • Zwart W; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research, London, SW7 3RP, UK.
  • Oesterreich S; Department of Molecular Pathology, Netherlands Cancer Institute, 1066CX, Amsterdam, Netherlands.
  • Carroll J; Department of Pharmacology and Chemical biology, University of Pittsburgh, Pittsburgh, PA, 15213, USA.
  • Ali S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, CB2 0RE, UK.
  • Dowsett M; Division of Cancer, CRUK Labs, University of London Imperial College, London, W12 0NN, UK.
Nat Commun ; 8(1): 1865, 2017 11 30.
Article en En | MEDLINE | ID: mdl-29192207
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Resistencia a Antineoplásicos / Receptor alfa de Estrógeno / Estradiol / Antagonistas del Receptor de Estrógeno Tipo de estudio: Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido
Texto completo
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XML
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Resistencia a Antineoplásicos / Receptor alfa de Estrógeno / Estradiol / Antagonistas del Receptor de Estrógeno Tipo de estudio: Risk_factors_studies Límite: Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Reino Unido