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Systematic screening of generic drugs for progressive multiple sclerosis identifies clomipramine as a promising therapeutic.
Faissner, Simon; Mishra, Manoj; Kaushik, Deepak K; Wang, Jianxiong; Fan, Yan; Silva, Claudia; Rauw, Gail; Metz, Luanne; Koch, Marcus; Yong, V Wee.
Afiliación
  • Faissner S; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Mishra M; Department of Neurology, St. Josef-Hospital, Ruhr-University Bochum, 44791, Bochum, Germany.
  • Kaushik DK; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Wang J; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Fan Y; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Silva C; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Rauw G; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Metz L; Neurochemical Research Unit, Department of Psychiatry, University of Alberta, Edmonton, AB, T6G 2B7, Canada.
  • Koch M; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
  • Yong VW; Department of Clinical Neurosciences, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, T2N 4N1, Canada.
Nat Commun ; 8(1): 1990, 2017 12 19.
Article en En | MEDLINE | ID: mdl-29259169
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Medicamentos Genéricos / Clomipramina / Encefalomielitis Autoinmune Experimental / Esclerosis Múltiple Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Medicamentos Genéricos / Clomipramina / Encefalomielitis Autoinmune Experimental / Esclerosis Múltiple Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Animals / Female / Humans Idioma: En Revista: Nat Commun Asunto de la revista: BIOLOGIA / CIENCIA Año: 2017 Tipo del documento: Article País de afiliación: Canadá