Mono-Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity.

McWhinnie, Fergus S; Sepp, Kristel; Wilson, Charlotte; Kunath, Tilo; Hupp, Ted R; Baker, Terry S; Houston, Douglas R; Hulme, Alison N

McWhinnie, Fergus S; Sepp, Kristel; Wilson, Charlotte; Kunath, Tilo; Hupp, Ted R; Baker, Terry S; Houston, Douglas R; Hulme, Alison N.

Afiliación

McWhinnie FS; EaStChem School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK.
Sepp K; MRC Centre for Regenerative Medicine, ISCR, University of Edinburgh, Edinburgh, EH16 4UU, UK.
Wilson C; EaStChem School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK.
Kunath T; EaStChem School of Chemistry, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, UK.
Hupp TR; MRC Centre for Regenerative Medicine, ISCR, University of Edinburgh, Edinburgh, EH16 4UU, UK.
Baker TS; Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XR, UK.
Houston DR; UCB Pharma Ltd., 208 Bath Road, Slough, SL1 3WE, UK.
Hulme AN; Institute of Quantitative Biology, Biochemistry and Biotechnology, University of Edinburgh, Edinburgh, EH9 3BF, UK.

Chemistry ; 24(9): 2094-2097, 2018 Feb 09.

Article en En | MEDLINE | ID: mdl-29267987

Palabras clave

NMR spectroscopy; peptides; ring-closing metathesis; stapled peptides; structure elucidation

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Texto completo: 1 Base de datos: MEDLINE Idioma: En Revista: Chemistry Asunto de la revista: QUIMICA Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido

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