A model of human lung fibrogenesis for the assessment of anti-fibrotic strategies in idiopathic pulmonary fibrosis.

Roach, Katy M; Sutcliffe, Amanda; Matthews, Laura; Elliott, Gill; Newby, Chris; Amrani, Yassine; Bradding, Peter

Roach, Katy M; Sutcliffe, Amanda; Matthews, Laura; Elliott, Gill; Newby, Chris; Amrani, Yassine; Bradding, Peter.

Afiliación

Roach KM; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK. kmr11@le.ac.uk.
Sutcliffe A; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Matthews L; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Elliott G; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Newby C; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Amrani Y; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.
Bradding P; Institute for Lung Health, Respiratory Medicine, Department of Infection, Immunity and Inflammation, University of Leicester, Leicester, UK.

Sci Rep ; 8(1): 342, 2018 01 10.

Article en En | MEDLINE | ID: mdl-29321510

Asunto(s)

Fibrosis Pulmonar Idiopática/etiología; Fibrosis Pulmonar Idiopática/metabolismo; Supervivencia Celular/genética; Células Cultivadas; Colágeno/metabolismo; Dexametasona/farmacología; Metabolismo Energético; Fibroblastos/efectos de los fármacos; Fibroblastos/metabolismo; Fibroblastos/patología; Perfilación de la Expresión Génica; Humanos; Fibrosis Pulmonar Idiopática/tratamiento farmacológico; Fibrosis Pulmonar Idiopática/patología; Inmunohistoquímica; Canales de Potasio de Conductancia Intermedia Activados por el Calcio/metabolismo; Modelos Biológicos; Técnicas de Cultivo de Tejidos; Transcriptoma; Factor de Crecimiento Transformador beta1/metabolismo

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Fibrosis Pulmonar Idiopática Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Sci Rep Año: 2018 Tipo del documento: Article País de afiliación: Reino Unido

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